schiff bases การใช้

• Schiff bases can be obtained by reacting amines with ketones or aldehydes.
• Similar methods are used to prepare Schiff bases and oximes.
• Chiral Schiff bases were one of the first ligands used for asymmetric catalysis.
• He was also interested in Schiff bases, described by his uncle Hugo Schiff.
• It readily forms Schiff bases with carbonyl groups.
• It is also used to produce Schiff bases with aldehydes, many of which are also used in perfumery.
• The aldehyde functional group is subject to nucleophilic attack, specifically by amines to form Schiff bases, which serve as bidentate ligands.
• This includes chemicals that : form irreversible bonds by electrophilic reaction; are metabolically activated by electrophiles; form Schiff bases with amino groups; and any type of a Michael acceptor.
• Such complexes do occur naturally, for instance in Corrin, but the majority of Schiff bases are artificial and are used to form many important catalysts, such as Jacobsen's catalyst.
• The free, uncharged aromatic amine groups then react with the aldehyde being tested to form two aldimine groups; these groups have also been named for their discoverer as Schiff bases ( azomethines ), with the usual carbinolamine ( hemiaminal ) intermediate being formed and dehydrated en route to the Schiff base.